BlastCrisis = European CML Blast Crisis Register [Czechia, Germany, Russian Federation, Ukraine]
Type of study
Other trial
Current status
Recruiting
Study title
European CML Blast Crisis Register (BlastCrisis)
Scientific title
European CML Blast Crisis Register (BlastCrisis) (ClinicalTrials.gov NCT03869502)
What is the purpose of the study
This is an observational study to collect data from patients with a CML blast crisis, either newly diagnosed or as evolution of a CML in chronic phase. The aim of the registry is to understand this rare condition better.
What will happen during the study
Key inclusion criteria
This registry is open to patients aged 18 years and older who have been diagnosed with BCR-ABL positive CML blast crisis according to the WHO criteria:
– Blasts 20% or more of peripheral blood white cells or bone marrow cells or
– Increase in the number of blast cells outside of the bone marrow (so-called extramedullary blast formation)
– Large foci or clusters of blasts in bone marrow biopsy
Patients can be included prospectively or retrospectively if they were treated on or after 01 May 2015.
Key exclusion criteria
Where can I find additional information
Study description in the US register ClinicalTrials.gov, a service of the U. S. National Institutes of Health
Study description in German on the website of Deutsche CML-Allianz
Study sponsor
University of Jena, Germany
Scientific lead / contact
Annamaria Brioli, PhD MD
Univerity of Jena, Germany
Principal investigator
Annamaria Brioli, PhD MD
Univerity of Jena, Germany
Study centers / principal investigators
Armenia
Details on study centers will be amended when available
Czechia
Masaryk University Hospital Brno
Brno, 62500
Prof. Dr. Jiri Mayer
France
Details on study centers will be amended when available
Germany
Universitätsklinikum Carl Gustav Carus an der Technischen Universität Dresden
Dresden, 01307
PD Dr. Christoph Röllig
Universitätsklinikum Essen
Essen, 45147
Dr. Joachim R. Göthert
University Hospital Jena
Jena, 07747
Annamaria Brioli, PhD MD
Universitätsklinikum Leipzig AöR
Leipzig, 04103
Dr. Georg-Nikolaus Franke
Universitätsmedizin Mannheim
Mannheim, 68169
Prof. Dr. Susanne Saussele
Universitätsklinikum Münster
Münster, 48149
Prof. Dr. Matthias Stelljes
Italy
Details on study centers will be amended when available
Poland
Details on study centers will be amended when available
Russian Federation
I. P. Pavlov First St. Petersburg State Medical University
Saint Petersburg, 197022
Dr. Elena Morozova, PhD
Serbia
Details on study centers will be amended when available
Spain
Details on study centers will be amended when available
Sweden
Details on study centers will be amended when available
Ukraine
National Research Center for Radiation Medicine
Kiev, 02000
Dr. Iryna Dyagil