EUREKA = ELN registry
Study title
EUREKA = ELN registry for patients with chronic myeloid leukemia (CML) in chronic phase (CP) who have been treated with tyrosine kinase inhibitors for at least two years
Scientific title
European survey on the assessment of deep molecular response in chronic phase CML patients after at least two years of therapy with tyrosine kinase inhibitors (EUREKA)
Type of study
Other trial = epidemiological registry
Current status
No longer recruiting
What is the purpose of the study
The EUREKA registry will collect and evaluate medical data and molecular results of the assessment of residual disease (deep molecular response, MR4.5) in patients with chronic myeloid leukemia (CML) in chronic phase (CP).
Deep molecular response is assessed routinely in the course of treatment of CML. Additional blood sampling will not be required.
Assessment results and biomaterials will be collected, stored and evaluated by specialized laboratories (certified MR4.5 labs). The data analysis is aiming to show the availability of deep molecular response assessment for all CML patients in Europe.
Key inclusion criteria
This European registry enrolls male or female patients from 18 years of age with a diagnosis of BCR-ABL positive CML in chronic phase (CP).
The registry will be available to all CML patients after at least two years of treatment with one or more tyrosine kinase inhibitor(s) (TKIs) at any prescribed dose as per routine clinical practice for a minimum of 24 months at registry entry.
Key exclusion criteria
Where can I find additional information
Study sponsor
European LeukemiaNet (ELN)
Scientific lead / contact
…
Principal investigator
Prof. Dr. med. Andreas Hochhaus
Universitätsklinikum Jena
Klinik Innere Medizin II
07740 Jena
Germany
Study centers / principal investigators
Participating countries:
Austria
Belgium
Bosnia-Herzegovina
Bulgaria
Croatia
Czech Republic
Denmark
France
Germany
Greece
Ireland
Italy
Lithuania
Norway
Poland
Portugal
Rumania
Slovenia
Spain
Switzerland
United Kingdom