MICROBIO-LMC = Interaction Between Gut Microbiota and TKIs in Patients With CML [Italy]

Study title

Interaction Between Gut Microbiota and TKIs in Defining the Clinical Outcomes of Patients With CML (MICROBIO-LMC)

Scientific title

Interaction Between Gut Microbiota and Tyrosine Kinase Inhibitors in Defining the Clinical Outcomes of Patients With Chronic Myeloid Leukemia

Type of study

Observational study

Phase

Not applicable

Current status

Recruiting

What is the purpose of the study

This is an observational study to assess the effects of gut microbiota, a collection of microorganisms in a person’s gastrointestinal system, on outcomes of treatment with tyrosine kinase inhibitors (TKIs) in patients with Chronic Myeloid Leukemia.

Key inclusion criteria

This study includes patients of all sexes who:

  • are aged 18 years and older.
  • have Chronic Myeloid Leukemia (CML) at any stage of the disease.

Further criteria may apply. Please discuss these with your doctor or study staff.

Key exclusion criteria

None

Estimated primary completion date

October 2026

Where can I find additional information

You can find a study description in the US register ClinicalTrials.gov, This is a database provided by the U. S. National Institutes of Health.

Study sponsor

Carmen Fava, University of Turin, in collaboration with Pfizer and Novartis

Scientific lead / contact

Carmen Fava, University of Turin

Principal investigator

Carmen Fava, Department of Clinical and Biological Sciences, University of Turin, Italy

Study centers / principal investigators

Italy

AO Ordine Mauriziano di Torino
Department of Clinical and Biological Sciences
Torino, 10128