TFR results and resources

TFR results and resources

Guidelines and Recommendations on Treatment-Free Remission in CML 

First recommendations exist about how to manage to stop and re-start therapy, based on early data from previous studies like the French STIM studies, the largest stop study EUROSKI as well as company-sponsored studies ENESTop, ENESTfreedom and DASFREE. The ELN, NCCN (USA) and ESMO (Europe) have published first recommendations for stopping treatment outside the context of clinical trials and the institutional requirements of the centre and lab. However, there is still no wide consensus among the CML experts, prognostic factors for TFR success are not yet clear, and the emotional impact is not yet well understood by doctors and patients.


Our publication in LEUKEMIA

tfr 1Our paper “Treatment-free remission in chronic myeloid leukemia: the patient perspective and areas of unmet needs” has been published in the scientific journal Leukemia in 2020.

Our TFR for CML patients’ study shows patient-based evidence on unmet needs of CML patients during the treatment-free remission journey.


Open Access Article in Leukemia:


Our full slide deck with TFR4CML survey data

TFR PPT deck

Our ESHCML2020 Abstract and Oral Presentation

TFR4CML results presented at the European School of Hematology, 22nd Annual John Goldman Conference on Chronic Myeloid Leukemia: Biology and Therapy.

Our Abstract Chronic Myeloid Leukemia Patients’ Concerns during Phase I of the Treatment-Free Remission Journey: Communication Between Patients and Doctors in the Different CML Advocates Network Regions” was accepted to be presented by our co-founder Giora Sharf as part of the scientific session 7: #TreatmentFreeRemission - Predictive factors".

Read the full Abstract  pdf ESHCML 2020 Abstract CMLAdvocatesNetwork (348 KB)


Our IACH2020 Abstract and Poster Presentation

Abstract and Poster presented at the International Academy for Clinical Hematology (IACH) 2020 Congress.

Read the Poster  pdf IACH2020 Poster CMLAdvocatesNetwork (1.36 MB)


Our EHA 2020 Abstract and Poster

Our Abstract CML Patients’ Views on Psychological Support Throughout the Treatment-Free Remission Journey” has been accepted at the 25th Congress of the European Hematology Association starting June 11.

EHA 2020 Abstract high 


Due to the COVID-19 outbreak, this year #EHA2020 has become a virtual event as have many other congresses, and the EHA Virtual Congress Platform will be accessible until October 15, 2020.

You can check in detail the E-Poster presented in EHA25Virtual by clicking in the image below:




ECRD online 1Our ECRD 2020 abstract and poster


We are happy to announce that the European Conference on Rare Diseases and Orphan Products 2020 has selected our abstract and poster "CML Patients’ Views on Psychological Support Throughout the Treatment-Free Remission Journey" to be presented at the conference that will take place online 14-15 May 2020.

TFR Poster ECRD 2020


The ECRD, organised by Eurodis and Orphanet, is recognised globally as the largest, patient-led rare disease event in which collaborative dialogue, learning and conversation takes place, forming the groundwork to shape future rare disease policies.


Abstracts 1Our ASH 2019 Abstract

The 61st American Society of Hematology Congress 2019 had selected our abstract "CML Patients’ Views on Psychological Support throughout the Treatment-Free Remission Journey" published online in the November supplemental issue of the prestigious magazine BloodTo read the full text of the Abstract "CML Patients’ Views on Psychological Support throughout the Treatment-Free Remission Journey", please click on the image on the right.


Our ASH 2019 Poster

Our Abstract has been additionally selected for Poster presentation as part of the scientific session 632 Chronic Myeloid Leukemia: Therapy: Poster II. Hematology Disease Topics & Pathways: Adult, Diseases, CML, Study Population, Myeloid Malignancies, taking place on Sunday, December 8, 2019, 6:00 PM-8:00 PM at Hall B, Level 2 (Orange County Convention Center), Orlando, USA.

To check and download the #ASH19 Poster "Chronic Myeloid Leukemia Patients’ Views on Psychological Support Throughout the Treatment-Free Remission Journey", please, click on the image below:

Poster 1



The authors would like to thank the 122 member organizations of the CML Advocates Network for their assistance in promoting the #TFR4CML survey and the CML patients who participated in the TFR for CML patients research.